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Whether you’re seeking restorative rest, nourishing rituals, or invigorating movement, our Inspiringly Mindful Retreat Room Packages offer tailored experiences that include daily breakfast, rejuvenating spa treatments, scenic cycling trails, and more—each designed to nurture body, mind, and spirit in the heart of the city.
Yes, PARKROYAL COLLECTION Marina Bay, Singapore features a 25-metre outdoor swimming pool that offers breathtaking views of the Marina Bay skyline.
Lung cancer is the second most common type of cancer occurring worldwide, affecting 2 million people every year, and over 1 million people die due to lung cancer each year. [ 1 - 3 ] About two-thirds of diagnoses of NSCLCs occur at an advanced or metastatic diseased stage; this makes the treatment planning approach more complex. [ 4 ] The subtypes of non-small-cell lung cancer (NSCLC) are diverse (Fig. 1 ).
Experience the adrenaline-driven thrill of the race, when you stay at PARKROYAL COLLECTION Marina Bay,Singapore located at the heart of the Marina Bay Street Circuit.
Anaplastic lymphoma kinase (ALK) is a potent oncogenic driver in lung cancer. ALK tyrosine kinase inhibitors yield significant benefit in patients with ALK fusion-positive (ALK + ) lung cancers; yet the durability of response is limited by drug resistance. Elucidation of on-target resistance mechanisms has facilitated the development of next-generation ALK inhibitors, but overcoming ALK-independent resistance mechanisms remains a challenge. In this Review, we discuss the molecular underpinnings of acquired resistance to ALK-directed therapy and highlight new treatment approaches aimed at inducing long-term remission in ALK + disease.
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